代谢综合征包括一些代谢性病理状态,如中心性肥胖、胰岛素抵抗、血脂异常、高血压、高血糖等。代谢综合征常伴发大血管病变,主要表现在心、脑血管疾病和外周血管疾病。研究表明,代谢综合征引起的内皮细胞功能紊乱与早期动脉粥样硬化及动脉粥样硬化性疾病有关联。现对血管内皮功能紊乱与动脉粥样硬化及代谢综合征相关性进行阐述。 Metabolic syndrome, including some metabolic pathological conditions, such as central obesity, insulin resistance, dyslipidemia, hypertension, high blood sugar and so on. Metabolic syndrome often associated with macrovascular disease, mainly in the heart, cerebrovascular disease and peripheral vascular disease. Studies have shown that metabolic syndrome-induced endothelial dysfunction is associated with early atherosclerosis and atherosclerotic disease. The vascular endothelial dysfunction and atherosclerosis and metabolic syndrome are described.