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目的:探讨高渗盐水(3.6%)联合沙丁胺醇雾化吸入治疗小儿毛细支气管炎的疗效。方法:选取2011年4月～2012年7月毛细支气管炎患儿96例,随机分为治疗组和对照组各48例,两组均采用相对的综合性治疗及一般的对症处理,在此基础上,对照组给予生理盐水联合沙丁胺醇雾化吸入,治疗组给予3.6%高渗盐水联合沙丁胺醇雾化吸入,评估两组临床治疗效果。结果:治疗组治愈率95.8%、对照组治愈率75.0%,与对照组比较,治疗组咳嗽消失时间、喘憋消失时间、心率恢复正常时间、肺部体征消失时间均优于对照组(P<0.05),两组疗效差异有统计学意义(P<0.05)。结论:在综合治疗基础上应用3.6%高渗盐水联合沙丁胺醇雾化吸入治疗小儿毛细支气管炎疗效肯定,既安全、有效,同时治疗费用低,可成为毛细支气管炎新的治疗方法,值得临床推广应用。
Objective: To investigate the therapeutic effect of hypertonic saline (3.6%) combined with albuterol inhalation on bronchiolitis in children. Methods: Ninety-six children with bronchiolitis from April 2011 to July 2012 were randomly divided into treatment group (48 cases) and control group (48 cases). The two groups were treated with relative comprehensive treatment and general symptomatic treatment, The control group was given inhalation of saline combined with salbutamol inhalation, the treatment group was given 3.6% hypertonic saline inhalation of salbutamol inhalation to evaluate the clinical efficacy of the two groups. Results: The cure rate of the treatment group was 95.8%, and the cure rate of the control group was 75.0%. Compared with the control group, the treatment group cough disappear time, wheezing disappear time, heart rate recovery time, lung signs disappear time were better than the control group (P < 0.05), the difference between the two groups was statistically significant (P <0.05). Conclusion: The treatment of infantile bronchiolitis with 3.6% hypertonic saline combined with inhalation of salbutamol is effective and safe on the basis of comprehensive treatment, which is safe and effective. At the same time, it can be a new treatment for bronchiolitis, which is worthy of clinical application .