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近来随着自由基生物学的发展,自由基的专一清除剂过氧化物歧化酶(Superoxide Dismutase,SOD)在疾病中的变化日益引起临床医学界的重视。本文旨在探讨脑出血时SOD变化及临床意义。1 对象与方法正常对照组80例,男50例,女30例,年龄40~60岁,平均年龄53.1岁。均为门诊体检、心电图、血三脂、胸透、二维超声心动图证实无急慢性疾病者。脑出血组40例,为随机选择1990~1991年经本科抢救治疗患者,全部符合1986年中华医学会第二次全国脑血管病学术会议脑出血诊断标准。观察一个月按转归分为:(1)死亡组19例,分别于发病后4小时~13天死亡,(2)成活组21例,包括由神志清楚、肢体活动基本恢复正常,到浅昏迷鼻饲
Recently, with the development of free radical biology, the change of superoxide dismutase (SOD), a free radical scavenger, has drawn increasing attention in the field of clinical medicine. This article aims to explore the changes of SOD in patients with intracerebral hemorrhage and its clinical significance. 1 objects and methods normal control group of 80 cases, 50 males and 30 females, aged 40 to 60 years, mean age 53.1 years. Outpatient examination, electrocardiogram, blood triglyceride, chest X-ray, two-dimensional echocardiography confirmed no acute and chronic diseases. Cerebral hemorrhage group of 40 patients were randomly selected from 1990 to 1991 underwent emergency treatment of patients, all in line with the 1986 Chinese Medical Association Second National Conference on Cerebral Vascular Disease diagnostic criteria for cerebral hemorrhage. The observation month was divided into: (1) 19 cases of death, were killed 4 to 13 days after onset, (2) Survival group of 21 cases, including conscious, physical activity returned to normal, to shallow coma Nasal feeding