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目的探讨胸腔镜肺癌根治术治疗肺癌的临床效果。方法选取2011年3月—2012年3月于厦门大学附属福州市第二医院行胸腔镜肺癌根治术治疗的肺癌患者39例作为观察组,另选取同期本院接受传统根治术治疗的40例肺癌患者作为参考组。比较两组患者心率、血压(舒张压、收缩压)、血氧饱和度(Sp O2)、手术时间、术中出血量、住院时间及并发症发生情况。随访5年,观察两组患者淋巴结转移情况及生存情况。结果治疗前两组患者心率、舒张压、收缩压、SpO_2比较,差异无统计学意义(P>0.05),治疗后观察组患者心率低于参考组,舒张压、收缩压、SpO_2高于参照组(P<0.05)。观察组患者手术时间和住院时间短于参考组,术中出血量少于参考组(P<0.05)。治疗后1年,观察组患者内淋巴结转移率比较,差异无统计学意义(P>0.05);治疗后2~5年,观察组患者淋巴转移率低于参照组(P<0.05)。观察组患者并发症发生率低于参照组(P<0.05)。两组患者5年生存率比较,差异无统计学意义(P>0.05)。结论胸腔镜肺癌根治术治疗肺癌的临床效果确切,对患者创伤小,术后患者恢复快。
Objective To investigate the clinical effect of thoracoscopic lung cancer radical resection for lung cancer. Methods From March 2011 to March 2012, 39 patients with lung cancer undergoing thoracoscopic lung cancer radical resection in Fuzhou Second Affiliated Hospital of Xiamen University were selected as the observation group. Another 40 patients with lung cancer undergoing radical resection Patient as a reference group. Heart rate, blood pressure (diastolic blood pressure, systolic blood pressure), blood oxygen saturation (Sp O2), operation time, intraoperative blood loss, hospital stay and complications were compared between the two groups. After 5 years of follow-up, lymph node metastasis and survival of the two groups were observed. Results There was no significant difference in heart rate, diastolic blood pressure, systolic blood pressure and SpO_2 between two groups before treatment (P> 0.05). After treatment, heart rate of observation group was lower than that of reference group, diastolic blood pressure, systolic blood pressure, SpO_2 was higher than that of reference group (P <0.05). The operation time and hospital stay in observation group were shorter than those in reference group, and the amount of bleeding during operation was less than that in reference group (P <0.05). One year after treatment, there was no significant difference in the rate of lymph node metastasis among the observation group (P> 0.05). After 2 to 5 years of treatment, the lymph node metastasis rate in the observation group was lower than that in the reference group (P <0.05). The incidence of complication in observation group was lower than that in reference group (P <0.05). There was no significant difference in the 5-year survival rates between the two groups (P> 0.05). Conclusions The clinical effect of thoracoscopic lung cancer radical surgery in the treatment of lung cancer is exact, with less trauma to patients and faster recovery after operation.