【摘要】背景辅助化疗对软组织肉瘤切除术后患者的疗效仍不确定。本研究旨在了解高强度辅助化疗对高危软组织肉瘤切除术后患者生存率的影响。方法本研究为多中心随机对照研究,入组标准包括肿瘤至少R1切除,Trojani分级Ⅱ至Ⅲ级,不限定肿瘤部位,无远处转移,体力状态评分小于2,年龄介于16至70岁之间、术后4周以内。患者被随机分 Abstract: The efficacy of background adjuvant chemotherapy in patients after soft tissue sarcoma resection remains uncertain. The purpose of this study was to understand the effect of high-intensity adjuvant chemotherapy on the survival rate of patients after high-risk soft tissue sarcoma resection. METHODS: This study was a multicenter randomized controlled study. The enrollment criteria included at least R1 resection of tumors, Trojani grades II to III, no limitation of tumor sites, no distant metastases, and performance status scores of less than 2 and ages between 16 and 70 years. Within 4 weeks after surgery. Patients were randomly assigned