胆汁反流性胃炎60例,随机分成多潘立酮治疗组30例(男性18,女性12;年龄43±5a)和甲氧氯普胺对照组30例(男性20,女性10;年龄41±4a)。用法均为10mg, tid, po, 4wk为一个疗程。结果:多潘立酮组胆汁反流消失26例(87％),有效率为90％,甲氧氯普胺组胆汁反流消失18例(60％),有效率67％。2组差异显著(P<0.05)。2组对临床症状的缓解无统计学差异。 Sixty patients with bile reflux gastritis were randomized into 30 domperidone-treated groups (18 males, 12 females; age 43 ± 5a) and 30 metoclopramide-treated patients (20 males and 10 females; 41 ± 4 years of age). Usage is 10mg, tid, po, 4wk for a course of treatment. Results: In the domperidone group, bile reflux disappeared in 26 cases (87%) and the effective rate was 90%. In the metoclopramide group, bile reflux disappeared in 18 cases (60%) and the effective rate was 67%. There was significant difference between the two groups (P <0.05). There was no significant difference in the relief of clinical symptoms between the two groups.