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为评价ＲＦＤ在短化中的效果，我们将２０５例初治菌阳肺结核病人，随机选入含ＲＦＰ与含ＲＦＤ两组短程化疗方案中，在全程监督下完成疗程，进行疗效及副作用的对照分析。结果：６个月疗程结束时，ＲＦＰ组痰菌阴转率为９９．０％，ＲＦＤ组为９０．０％，无显著差异（Ｐ＞０．０５），随访２年痰菌复阳率，ＲＦＰ组为５．０％，ＲＦＤ组为２０．２％，两组有显著差异（Ｐ＜０．０１）其它如肺部病灶改变及副反应两组均无明显差异。认为，ＲＦＤ的正式推广应用值得考虑。
In order to evaluate the effect of shortening of RFD, 205 patients with newly diagnosed bacillary positive pulmonary tuberculosis were randomized into two groups of short-course chemotherapy regimens containing RFP and RFD. The course of treatment was completed under the supervision of the whole procedure, and the efficacy and side effects were compared . Results: At the end of 6 months, sputum negative conversion rate was 99.0% in RFP group and 90.0% in RFD group, no significant difference (P> 0.05) RFP group was 5.0%, RFD group was 20.2%, there was a significant difference between the two groups (P <0.01) other lung lesions such as changes and side effects were no significant difference between the two groups. That the formal promotion of RFD applications worth considering.