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苯海拉明(下简称DPH)在猫、豚鼠、狗以及人体,对各种刺激方法引起的实验性咳嗽,均有止咳作用。本文采用双盲法,客观评价DPH对人体病理性咳嗽的镇咳效力。观察方法14名患者(男7女7),平均年龄为50.7岁(24—74岁),一律住院观察。每个病人以双盲法,随机顺序,分为三组,分别服用DPH50mg,25mg或安慰剂,从早上8时开始,每4/小时服药一次,每日共4次。用药前至少观察两天,选出咳嗽次
Diphenhydramine (hereinafter referred to as DPH) in cats, guinea pigs, dogs and the human body, all kinds of stimulation caused by experimental cough, have cough. In this paper, double-blind method, an objective evaluation of DPH on human pathological cough antitussive effect. Observation method 14 patients (7 males and 7 females) with an average age of 50.7 years (24-74 years), all hospitalized. Each patient was divided into three groups in a double-blind, randomized fashion, taking DPH 50 mg, 25 mg, or placebo, starting at 8 a.m. every 4 / hr, 4 times a day. At least two days before treatment, cough times were selected