论文部分内容阅读
目的探讨逐瘀通淋汤与抗生素联合应用治疗经尿道前列腺切除术后下尿路刺激症状的疗效。方法选择行经尿道前列腺切除术且术后拔除导尿管伴有尿路刺激症状的患者120例,随机分为治疗组和对照组,每组各60例。治疗组接受中西医药治疗方法(逐瘀通淋汤100ml2次/d口服,同时应用广谱抗生素),对照组用西医治疗方法(单纯应用广谱抗生素),两组疗程均为7d。分别于治疗前、后以患者排尿的症状而影响生活质量评分(BS)与排尿日记记录(平均每次尿量、24h平均排尿次数)、国际LUTS症状程度轻、中、重评分和最大尿流率为疗效评判标准评价两组疗效。结果治疗7d后,治疗组总有效率为90.00%,对照组总有效率76.67%,治疗组总有效率明显优于对照组(P<0.05);治疗前后影响生活质量评分(BS)、24h排尿次数、平均每次排尿量及国际LUTS评分比较,治疗组均优于对照组(P<0.05);两组患者治疗前后最大尿流率(Qmax)均比治疗前有明显改善(P<0.05),但治疗组与对照组改善尿流率疗效差异无统计学意义(P>0.05)。结论逐瘀通淋汤是治疗经尿道前列腺切除术后下尿路症状的安全、有效的方药。
Objective To investigate the therapeutic effect of Zhuyu Tongling Decoction combined with antibiotics on lower urinary tract irritation after transurethral resection of prostate. Methods A total of 120 patients undergoing transurethral resection of the prostate and postoperative catheterization with urinary tract irritation were randomly divided into treatment group and control group, 60 cases in each group. The treatment group received Chinese and Western medicine treatment (Zhuyu Tonglin decoction 100ml 2 times / d orally, at the same time the application of broad-spectrum antibiotics), the control group treated with Western medicine (simple use of broad-spectrum antibiotics), the two courses of treatment were 7d. (BS) and diuresis records (average urine output, average urination 24h), symptoms of mild LUTS, moderate and severe scores, and maximum urinary flow in patients with urinary symptoms before and after treatment The rate of efficacy evaluation criteria for the evaluation of two groups of curative effect. Results After treatment for 7 days, the total effective rate was 90.00% in the treatment group and 76.67% in the control group, and the total effective rate in the treatment group was significantly better than that in the control group (P <0.05); before and after treatment, the quality of life score (BS) (P <0.05). The maximal urinary flow rate (Qmax) before and after treatment in both groups were significantly improved compared with those before treatment (P <0.05), the average urinary output per time and the international LUTS score were higher in the treatment group than those in the control group , But there was no significant difference between the treatment group and the control group in improving the urinary flow rate (P> 0.05). Conclusion Zhuyu Tongling Decoction is a safe and effective prescription for the treatment of lower urinary tract symptoms after transurethral resection of prostate.