近十年来,随着视神经轴浆运输的同位素放射自显影、神经组织化学以及电镜研究的开展,对一些视乳头病变的病理变化和发病机制的认识,已进入一个新的层次。如颅内压增高性视乳头水肿;青光眼的视神经损害;低眼压性视乳头水肿;缺血性视乳头病变;视神经萎缩等,都与视神经的轴浆运输有着极密切的联系。本文根据文献中的报道,简略介绍各种视神经损害的动物实验研究。一、视神经的轴浆运输视神经轴突内轴浆的流动,按其运动方向可 In the last decade, with the autoradiography of isotope autoradiography of optic axonal transport, neurohistochemistry and the development of electron microscopy, the understanding of the pathological changes and pathogenesis of some optic nerve lesions has entered a new level. Such as increased intraocular pressure papilledema; glaucomatous optic nerve damage; hypotony papilloedema; ischemic optic disc disease; optic atrophy, etc., are closely linked with the axoplasmic transport of the optic nerve. In this paper, according to reports in the literature, a brief introduction of various experimental studies of optic nerve damage. First, the optic nerve axoplasm transport axonal pulp optic nerve flow, according to the direction of their movement can be