The mammalian target of rapamycin (mTOR) is a major component of the PI3K/AKT signaling pathway that is dysregulated in 50% of all human malignancies.Rapamy
The breast cancer tumor suppressor, BRCA1, is mutated in many familial breast cancers and functions in the cell nucleus and at the centrosome to regulate DN
In the last decade the number of breast cancer patients presenting with early stage disease has increased.The results from multiple randomized breast cancer