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血小板增多症可发生在炎症性肠病时,可能代表对炎症的一个非特异性反应。作者已观察到活动性克隆病血小板计数升高,因此进一步研究血小板计数是否为克隆病疾病活动的一个有用指标。 57例克隆病为研究对象,男27、女30例,平均年龄37±14岁。平均病程9年。放射学检查病变部位分布情况。弥漫性小肠(9),回盲肠(24),回结肠(8),结肠(13),肛门直肠(3)。30例曾行切除术,22例复发。26例在用强的松龙、15例在用柳氮磺胺吡啶治疗。疾病的活动性通过一个简便的临床指数评价。全部病人均应用自动化技术Clay Adams Ultra Flo100全血血小板计数器检测血小板(正常150～450×100/L)。大多数患者应用自动Beckman速率比浊计测定血清类粘蛋白(orosomucoid)浓度(正常<1.0g/L)。
Thrombocytosis, which can occur in inflammatory bowel disease, may represent a nonspecific response to inflammation. The authors have observed an elevated platelet count in patients with Crohn’s disease and therefore further study whether platelet count is a useful indicator of disease activity in Crohn’s disease. 57 cases of Crohn’s disease as research object, 27 males and 30 females, with an average age of 37 ± 14 years. The average duration of 9 years. Radiological examination of lesions distribution. Diffuse small intestine (9), ileocecal (24), back colon (8), colon (13), anorectal (3). 30 cases had resection, 22 cases of recurrence. Twenty-six patients were treated with prednisolone and 15 patients were treated with sulfasalazine. Disease activity is assessed by a simple clinical index. All patients were tested for platelets using Clay Adams Ultra Flo100 whole blood platelet counter (normal 150-450 × 100 / L). Most patients use an automatic Beckman rate nephelometer to measure serum orosomucoid concentrations (normal <1.0 g / L).