高密度寡核苷酸DNA芯片技术可以通过一次杂交试验获得大量的基因组信息,在基因组结构与基因表达分析中应用最广,在与人类健康有关的遗传病、传染病等许多疾病中具有广泛的应用前景。本文重点对基因芯片技术在细菌、病毒等致病微生物病原鉴定、分类与致病机制研究中的应用作一简要介绍。 High-density oligonucleotide DNA chip technology can obtain a large amount of genome information through a hybridization test, and has the most extensive application in genomic structure and gene expression analysis, and has a wide range of diseases such as hereditary diseases and infectious diseases related to human health Application prospects. This article focuses on the gene chip technology in bacteria, viruses and other pathogens identification, classification and pathogenesis of the application of a brief introduction.