子宫内膜浆液性乳头状癌(UPSC)是子宫内膜癌的一种特殊类型,有着独特的生物学行为和病理特征。其发病率较低,但恶性度高,预后差。目前,该病的危险因素、预后因素尚不确定,术前诊断率低,发病机制亦无定论,治疗仍处于探索阶段。对国外近5年在UPSC的病因、诊断、治疗等方面新的理念、方法作文献综述。 Endometrial serous papillary carcinoma (UPSC) is a special type of endometrial cancer, has a unique biological behavior and pathological features. The incidence is low, but the high degree of malignancy, the prognosis is poor. At present, the disease risk factors, prognostic factors are not yet determined, preoperative diagnosis is low, the pathogenesis is inconclusive, the treatment is still in the exploratory stage. In the past five years abroad, the essay summarizes the new ideas and methods in the etiology, diagnosis and treatment of UPSC.