近年来免疫抑制方法的新进展共有以下四项: 一、Cyclosporin A的发现: 皮质类固醇6-氢硫基嘌呤和硫唑嘌呤的重要发现能改变移植体的免疫反应,但又没有完全消灭宿主的防御机能,在临床上给同种移植开拓了道路,针对这一目标在各种免疫抑制药物的竞争中,有些很快掉了队,而Cyclophosphamide则独树一帜。此药在1976年由真菌(Cylindrocorpum lucidum及Tri- In recent years, there have been four new advances in immunosuppressive methods. First, the discovery of Cyclosporin A: The important discovery of corticosteroids 6-thiothiopurine and azathioprine can change the immune response of the graft, but it does not completely eliminate the host’s The defensive function has opened up the way for the same kind of transplantation in the clinic. Some of the competition in various immunosuppressive drugs against this goal has quickly dropped out of the team, and Cyclophosphamide is unique. This medicine was made in 1976 by the fungus (Cylindrocorpum lucidum and Tri-