进入80年代以来,随着生物化学,分子生物学和免疫学的发展,新的研究手段不断产生。在高血压病因学研究中,对高血压发病的神经内分泌机理的研究更加广泛、深入。除对肾素—血管紧张素系统(renin-angiotensinsystem,RAS)外,又对内源性洋地黄物质,心房钠尿多肽及加压素等在高血压形成中的作用进行了研究。就RAS的研究而言,也更加深化,即从循环中RAS的研究进入局部组织(血管、脑等等)的RAS的研究。使该系统在高血压形成中的意义更加明了。由于神经内分泌系统对免疫调节研究的深入,发现某些激素(如胸腺素)可以通过对高血压动物的免疫调节而降压。血管紧张素(ANG),去甲肾上腺素(NE),这些影响血压的激素也可以影响免 Since the 1980s, with the development of biochemistry, molecular biology and immunology, new research methods are constantly emerging. Etiology in the study of hypertension, the pathogenesis of hypertension neuroendocrine mechanism of research more extensive and in-depth. In addition to renin-angiotensin system (renin-angiotensin system, RAS), but also on the endogenous digitalis matter, atrial natriuretic peptide and vasopressin in the role of hypertension in the study. As far as the RAS study is concerned, RAS research into the local tissues (blood vessels, brain, etc.) from the RAS research in circulation is further deepened. Make the system more meaningful in the formation of hypertension. Due to the neuroendocrine system on immune regulation in-depth study and found that some hormones (such as thymosin) can be antihypertensive animal immunosuppression and antihypertensive. Angiotensin (angiotensin) (ANG), norepinephrine (NE), these hormones affect blood pressure can also affect