本文对30例未治疗过的巨幼细胞性贫血,包括恶性贫血27例,胃部分切除后的维生素B_(12)缺乏2例及有维生素B_(12)特异性吸收不良的1个3(1/2)岁男孩和正常对照22例进行了血清铁蛋白及有关血液学检查,以衡量巨幼细胞性贫血时铁的存在情况。受检者除1例儿童外,均为45～80岁的成人。结果示27例恶性贫血病人的平均血清铁蛋白(330ng/升)与22例正常对照(164ng/升)之间存在显著性差异(P<0.05>0.02)。 In this paper, 30 cases of untreated megaloblastic anemia including 27 cases of pernicious anemia, 2 cases of vitamin B 12 deficiency after partial gastric resection and 1 case of 3 (1 / 2) year old boy and normal control in 22 cases of serum ferritin and related hematology to measure the presence of iron in megaloblastic anemia. Subjects except one child, are 45 to 80-year-old adult. The results showed that there was a significant difference (P <0.05> 0.02) between the mean serum ferritin (330 ng / L) and 22 normal controls (164 ng / L) in 27 patients with pernicious anemia.