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目的通过检测血清载脂蛋白水平,观察肝硬化患者肝功能损害程度,为肝硬化的诊断提供依据。方法采用日立7600-020型全自动生化分析仪测定血清ApoA1、ApoB及肝功能,并进行Child-Pugh分级。结果肝硬化患者血清ApoA1、ApoB显著低于正常对照组。结论检测血清ApoA1、ApoB水平对肝硬化的诊断、肝功能分级及判断预后有重要的临床意义。
Objective To detect the level of apolipoprotein in serum and observe the degree of liver damage in patients with cirrhosis and provide basis for the diagnosis of cirrhosis. Methods Serum ApoA1, ApoB and liver function were measured by Hitachi 7600-020 automatic biochemical analyzer and were graded by Child-Pugh. Results The serum levels of ApoA1 and ApoB in patients with cirrhosis were significantly lower than those in normal controls. Conclusion The detection of serum ApoA1, ApoB levels have important clinical significance in the diagnosis of liver cirrhosis, grading of liver function and prognosis.