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兔感染日本血吸虫尾蚴４８－５２条，每ｗｋ１次，共６次，并于第１次感染后ｄ７ｉｇ１次蒿甲醚（Ａｒｔ）１０ｍｇ．ｋｇ－１，然后每１或２ｗｋ重复ｉｇ１次相同剂量的Ａｒｔ，连给８或４次时，减♀虫率各为９７．８％和８８．９％；上述兔于第１次感染后ｄ２１ｉｎｌ次吡喹酮（Ｐｒａ）４０ｍｇ．ｋｇ－１，然后每１或２ｗｋ重复ｉｇ１次相同剂量的Ｐｒａ，连给７或４次的♀虫率减少率均为１００％。兔每隔１ｄ感染１次血吸虫尾锄４８－５２条，共５次，并于第１次感染后ｄ７ｉｇ１次Ａｒｔ１０ｍｇ．ｋｇ－１，然后每ｗｋ重复给药１次，连给５次的减♀虫率为９５．１％，但受治的４只兔仍残留♀虫，而每２ｗｋ重复给药１次，连给３次的减♀虫率为７８．２％。将每次ｉｇ的Ａｒｔ剂量增至１５ｍｇ．ｋｇ－１，则每ｗｋ给药组的６兔中，４兔无♀虫，减♀虫率为９８．４％，每２ｗｋ给药１次的５兔中，２兔无♀虫，减丰虫率为９７．６％。上述兔于第１次感染后ｄ２１ｉｇ１次Ｐｒａ４０ｍｇ·ｋｇ－１，然后每１或２ｗｋ重复ｉｇ１次相同剂量的Ｐｒａ，连给３或２次的减♀虫率各为９９．１％和９８．２％。在各组受治的５兔中，各有４及１兔无♀虫。将每次ｉｇＰｒａ的剂量减至３０ｍｇ．ｋｇ－１，则?
Rabbits infected with 48-52 Schistosoma japonicum cercariae every wk1 times for 6 times, and after the first infection d7ig1 Artemether (Art) 10mg. kg-1, and then every 1 or 2wk ig 1 times the same dose of Art ig, even to 8 or 4 times, the reduction of worm rates of 97.8% and 88.9% respectively; rabbits in the first infection d21inl Praziquantel (Pra) 40mg. kg-1, and then repeated every 1 or 2wk ig 1 the same dose of Pra, even to 7 or 4 times the rate of reduction of pinworm were 100%. Rabbits were infected once every 1d schistosome tail hoe 48-52, a total of 5 times, and after the first infection d7ig1 Art10mg. kg-1, and then repeated once every wk administration, even to 5 times the reduction of the rate of worm was 95.1%, but the treated 4 rabbits remained pinworm, and repeated every 2wk administration 1, and even To 3 times the reduction of the worm rate was 78.2%. Increase the Art dose for each ig to 15 mg. kg-1, there was no pinworm in 6 rabbits per wk administration group, no reduction of pinworm, 98.4% reduction in worm burden, no rabbits in 2 rabbits administered once every 2 weeks, The worm rate was 97.6%. The rabbits were given Pra21 mg once a day at 40 mg · kg -1 d21ig1 after the first infection, and then the same dose of Pra was repeated 1 or 2 weeks for 1 or 2 weeks, and the rates of reduction to 3 or 2 times were 99.1% and 98.2, respectively %. Of the 5 rabbits in each group, 4 and 1 rabbits each had no vermin. Reduce the dose of igPra to 30 mg each time. kg-1, then?