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目的观察无创正压通气(NPPV)对肺源性呼吸困难的尘肺病患者康复治疗效果。方法采用回顾性分析方法,对295例住院接受NPPV治疗的尘肺病患者的治疗依从性、治疗时间、治疗效果及不良反应进行分析。结果295例尘肺病患者接受NPPV治疗时间的中位数为14(1~281)d。治疗依从性良好率为79.66%(235/295);呼吸困难改善率为73.22%(216/295),趋势性2检验结果显示,随治疗时间延长,患者呼吸困难改善率增加(P<0.01);其中,治疗时间10~d组、20~d组、≥30 d组患者呼吸困难改善率均高于<10 d组(P<0.01),≥30 d组患者高于10~d组(P<0.01)。治疗过程中不良反应发生率为7.12%。结论 NPPV治疗可较好地改善尘肺病患者呼吸困难症状,不良反应少。
Objective To observe the effect of noninvasive positive pressure ventilation (NPPV) on rehabilitation of pneumoconiosis patients with pulmonary-derived dyspnea. Methods The retrospective analysis was used to analyze the treatment compliance, treatment time, treatment effect and adverse reactions of 295 pneumoconiosis patients who were hospitalized with NPPV. Results The median time to NPPV treatment in 295 patients with pneumoconiosis was 14 (1-281) days. The compliance rate of treatment was 79.66% (235/295). The improvement rate of dyspnea was 73.22% (216/295). The trend 性2 test showed that the improvement rate of dyspnea was increased with the prolongation of treatment time (P <0.01) ); Among them, the improvement rate of dyspnea in the 10 ~ d group, the 20 ~ d group and the ≥30 d group were higher than those in the <10 d group (P0.01), those in the ≥30 d group were higher than those in the 10 ~ d group P <0.01). The incidence of adverse reactions during treatment was 7.12%. Conclusion NPPV treatment can improve the symptoms of dyspnea in patients with pneumoconiosis with less adverse reactions.