甲巯咪唑 (ｔｈｉａｍａｚｏｌｅ)是临床常用的硫脲类抗甲状腺药 ,由于该类药物口服给药疗程较长 ,长期口服可以出现血粒细胞缺乏及肝功能异常等严重不良反应而终止治疗。将其制成透皮吸收乳膏 ,并加入高效促渗剂月桂氮酮 ,以提高药物疗效 ,降低不良反应。作者报告甲巯咪唑乳 Thiamazole is a clinically used thiourea antithyroid drug. Due to the long course of oral administration of such drugs, long-term oral administration can stop the treatment due to severe adverse reactions such as hemagglutination and abnormal liver function. It will be made into transdermal absorption cream, and join the high efficiency penetration enhancer lauropelitazone, in order to improve the efficacy of drugs and reduce adverse reactions. The authors report methimazole milk