丙二酸和醛酮按Knoevenagel反应缩合生成α-烯酸,催化剂通常用吡啶等碱性物质。反应后需分离、回收催化剂和提取产物,步骤颇为繁杂。作者发现芳醛和丙二酸在分子筛催化下极易得到取代苄叉丙二酸化合物;脂肪醛和丙二酸在载有三乙胺的分子筛催化下,可得到β-烯酸,选择性高,是合成β-烯酸的简便方法。 Malonate and aldehyde ketones by Knoevenagel reaction condensation α-acid, the catalyst usually pyridine and other alkaline substances. After the reaction to be separated, the catalyst recovery and product extraction, the procedure is rather complicated. The authors found that arylaldehyde and malonic acid can be easily substituted benzylidene malonic acid compounds under the molecular sieve catalysis; fatty aldehydes and malonic acid can be obtained by the molecular sieve containing triethylamine catalysis, high selectivity, It is a convenient way to synthesize β-enoic acid.