作者复习了抗凝治疗引起神经系统并发症的有关文献并总结指出:抗凝剂引起的出血可累及神经系统的任何部位,可在无外伤的情况下并且在凝血酶原时间、凝血时间或部分凝血活酶时间均在可接受治疗范围内的情况下,由双香豆素或肝素等抗凝剂引起,这种情况可能与其他抗凝作用的因子如Ⅶ、Ⅸ或Ⅹ等因子的机能降低,或与不被病人意识到的神经系统轻微外伤有关。颅内出血是抗凝剂治疗时引起死亡的主要原因,以硬膜下血肿发病率最高(占全部硬膜下血肿病例的12～38％),其次为脑出血,其他部位如蛛网膜下腔出 The authors reviewed the literature on anticoagulation-induced neurological complications and concluded that hemorrhaging caused by anticoagulants can affect any part of the nervous system without the risk of trauma and during prothrombin time, clotting time or fractional Thromboplastin time is within acceptable treatment range, caused by anticoagulants such as dicoumarol or heparin, which may be related to other anticoagulant factors such as Ⅶ, Ⅸ or Ⅹ reduced the function of factors , Or minor traumas of the nervous system that are not perceived by the patient. Intracranial hemorrhage is the main cause of death from anticoagulant therapy, with the highest incidence of subdural hematoma (12 to 38% of all cases of subdural hematoma), followed by cerebral hemorrhage, other sites such as subarachnoid space