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本研究旨在进一步证实丙戌酸对小舞蹈病的疗效。方法在18个月期间,因中度小舞蹈病而来院就诊的全部患儿均给予丙成酸钠治疗,于1周以后达到15～20mg/kg/d剂量,井于治疗期结束时逐渐停用(超过1周)。小舞蹈病诊断主要根据临床。全部患者均行常规血液学和生化,ASO滴度,血清铜和血浆铜蓝蛋白,C-反应蛋白浓度,循环免疫复合物,抗核抗体,血清蛋白电泳,血清补体浓度,甲状腺功能试验,胸部X线和ECG检查。如2周内无明显效果,则停用丙戊酸钠。如有不完全缓解,则加用苯巴比妥。虽早期效果良好,仍需继续治疗4～8周。于
The purpose of this study is to further confirm the effect of propionate on small chorea. Methods All children who had been hospitalized for mild to moderate chorea were treated with sodium valproate at 18 months. After 1 week, the dosage reached 15-20 mg / kg / d, and gradually stopped at the end of the treatment period Used (more than 1 week). Small chorea diagnosis is mainly based on clinical. All patients underwent routine hematology and biochemistry, ASO titers, serum copper and ceruloplasmin, C-reactive protein concentrations, circulating immune complexes, antinuclear antibodies, serum protein electrophoresis, serum complement concentrations, thyroid function tests, chest X-ray and ECG examination. If no significant effect within 2 weeks, then discontinued sodium valproate. If not completely relieved, then add phenobarbital. Although early effect is good, still need to continue treatment for 4 to 8 weeks. in