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目的对他汀类药物与心血管药物配伍的安全性进行分析。方法将2014年4月—2015年4月入我院治疗慢性心力衰竭的60例患者作为研究对象,将其按照比例随机分为试验组与对比组,每组各30例,给予对比组进行常规治疗(包括化痰止咳、利尿强心等,试验组在此基础上口服辛伐他汀,观察2组的治疗情况并记录是否有不良反应产生。结果试验组治疗总有效率显著高于对比组,差异具有统计学意义(P<0.05)。结论他汀类药物与其他心血管药物配伍的安全性较高,但仍需继续注意药物搭配使用时的相互作用,避免不良反应发生。
Objective To analyze the safety of compatibility of statins with cardiovascular drugs. Methods Sixty patients with chronic heart failure who were admitted to our hospital from April 2014 to April 2015 were selected as study subjects and randomly divided into experimental group and control group with 30 cases in each group, The treatment group (including Huatanzhike, diuretic cardia, etc.), the experimental group on the basis of oral simvastatin, observe the treatment of two groups and record whether there are adverse reactions.Results The total effective rate of the experimental group was significantly higher than the control group, (P <0.05) .Conclusion The compatibility of statins with other cardiovascular drugs is high safety, but still need to continue to pay attention to the interaction of drugs with the use of to avoid adverse reactions.