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可溶性白细胞介素2受体(Soluble Inteleukin-2receptor, SIL-2R)是活化的T细胞膜上的●肽链成份,是反映T细胞激活的可溶性标志,与许多疾病的病情及预后密切相关。许多研究发现,机体免疫功能改变既与脑动脉硬化有关,也与脑血管病发生后的病理改变有关。本研究通过双抗体夹心ELISA法检测54例脑梗塞患者血清SIL-2R水平,目的在于探讨其在脑梗塞发生后的作用及其临床意义。 1 资料与方法 1.1 研究对象 脑梗塞组:54例,男29例,女25例;年龄45～85岁,平均63.28±12.82岁。均为我院神经科初次发病的住院患者。诊断符合第二届全国脑血管病学术会议所制定的标准,并经头颅CT证实。脑梗塞体积采用多田公式计算;T=π/6×长轴×短轴×层面厚度。伴有免疫性及感染性疾病以及应用了影响免疫功能药
Soluble Interleukin-2 receptor (SIL-2R) is a peptide component of activated T cell membrane. It reflects soluble sign of T cell activation and is closely related to the condition and prognosis of many diseases. Many studies have found that changes in immune function not only with cerebral arteriosclerosis, but also with pathological changes after cerebrovascular disease. In this study, 54 patients with cerebral infarction serum SIL-2R levels by double antibody sandwich ELISA, the purpose is to explore its role in cerebral infarction and its clinical significance. 1 Materials and Methods 1.1 The study group of cerebral infarction: 54 cases, 29 males and 25 females; aged 45 to 85 years, mean 63.28 ± 12.82 years. Are hospital for the first time in our department of neurology inpatients. Diagnostic meet the second session of the National Conference on cerebrovascular disease standards set by the head CT confirmed. The infarct volume was calculated using the Tada formula; T = π / 6 × major axis × minor axis × slice thickness. Accompanied by immune and infectious diseases and the application of immune function drugs