报告1例口服多西环素胶囊后食管溃疡。患者女,26岁。患者因寻常痤疮口服多西环素胶囊,2 d后出现胸骨后疼痛、吞咽疼及吞咽困难,结合电子胃镜和组织病理检查诊断为食管溃疡。停用多西环素,给予胃黏膜保护剂、质子泵抑制剂等对症治疗后食管黏膜恢复正常。 One case of oral administration of doxycycline capsules reported esophageal ulcer. Female patient, 26 years old. Patients with oral acyclidine doxycycline capsules, 2 days after the occurrence of post-sternal pain, swallowing pain and swallowing difficulties, combined with electronic endoscopy and histopathological examination of esophageal ulcers. Disable doxycycline, given gastric mucosal protective agent, proton pump inhibitors symptomatic treatment of esophageal mucosa returned to normal.