论文部分内容阅读
目的探讨胸上段食管癌同步整合加量调强放射治疗逆向计划与正向计划的剂量学差异。方法对10例胸上段食管癌患者分别设计静态逆向调强同步集合推量与静态正向调强野中野肿瘤区同步加量两种放射治疗计划,比较两种计划的靶区剂量、危及器官的受照剂量体积差异等指标。结果两种计划均能满足临床剂量学要求。逆向计划的适形指数、剂量均匀指数、最大剂量、最小剂量、平均剂量、靶区接受剂量95%等剂量线所包括的体积百分比、脊髓最大剂量、平均肺剂量以及肺接受20、30Gy照射的肺体积占全肺总体积的百分比均优于正向计划(P<0.01或P<0.05)。而正向计划的肺接受5Gy照射的肺体积占全肺总体积的百分比及子野数目、总跳数、治疗时间、计划设计时间均优于逆向计划(P<0.01)。结论同步整合加量逆向调强放射治疗技术可能是胸上段食管癌患者行根治性放射治疗的更好选择。
Objective To investigate the difference of dosimetry in reverse plan and forward plan of upper thoracic esophageal cancer with concurrent dose-plus-dose radiation therapy. Methods Ten patients with upper thoracic esophageal cancer patients were designed to set the amount of static reverse ostensor synchronously and the amount of synchrotron radiation in the medial field of the static forward intensity modulated field radiation dose. The dose of the two planned targets and the risk of organ damage According to dose volume differences and other indicators. Results Both plans met clinical dosimetry requirements. Reverse planned conformal index, even dose index, maximum dose, minimum dose, average dose, target volume received 95% of the dose line volume percentage, the maximum spinal cord dose, the average lung dose and lung exposure to 20,30 Gy The percentage of lung volume to total lung volume was superior to the forward plan (P <0.01 or P <0.05). The percentage of total volume of lungs and the total number of subfields, the total number of hops, the duration of treatment and the planned design time of 5Gy lungs receiving forward planned lungs were all better than that of reverse plans (P <0.01). Conclusions Simultaneous integration and dosage of IMRT may be a better choice for radical thoracic radiotherapy for patients with upper thoracic esophageal cancer.