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比较了6种新生儿血源乙型肝炎疫苗的免疫方案,其中一种只免疫HBsAg阳性母亲的婴儿效果最差,群体有效率仅17.79％,成本效益比值亦低。其它5种方案都是对全部新生儿进行免疫,效果均好。这5种方案是10μg与3μg两种剂量的不同组合,其中用10μgg3JI疫者成本效益比值最高,有效率为78.61％。HBsAg阳性母亲新生儿按30μg×3,而阴性母亲婴儿首剂用30μg,第2、3剂各10μg,有效率高达87.47％,但成本效益比值最低。应根据我国经济发展的水平与群众的承受能力,对各地区选用不同的新生儿免疫方案。
Six kinds of neonatal blood-borne Hepatitis B vaccine immunization programs were compared. Among them, only one infant immunized with HBsAg-positive mothers had the worst effect, with a population-effective rate of only 17.79% and a low cost-benefit ratio. The other five programs are all newborn immunization, the effect is good. The five programs are different combinations of two doses of 10μg and 3μg, of which 10μggg3JI the highest cost-benefit ratio of the highest, the effective rate was 78.61%. HBsAg-positive mothers at 30μg × 3 newborns, while the negative mother’s first dose of 30μg, second and third doses of 10μg, the effective rate of up to 87.47%, but the lowest cost-effectiveness ratio. According to the level of economic development in our country and the capacity of the masses, different neonatal immunization programs should be selected for all regions.