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用表面灌流法,在有、无外源性混合气体的条件下,比较乙酰胆碱引起的豚鼠胃纵、环肌最大收缩(Cmax)、半数有效量(ED_(50))和营养液pH值的变化。结果:有、无外源性混合气体,对豚鼠胃各部纵、环肌的Cmax、ED_(50)无明显影响;营养液pH值无明显的变化。
The changes of Cmax, half effective dose (ED_ (50)) and pH value of nutrient solution induced by acetylcholine in guinea pigs were compared by surface perfusion with and without exogenous gas mixture . Results: No exogenous gas mixture had significant effect on Cmax and ED_ (50) in the longitudinal and circular muscle of guinea pig stomach. There was no obvious change in the pH of nutrient solution.