论文部分内容阅读
目的探讨急性垂体卒中患者在经蝶手术前后的垂体功能的变化情况。方法回顾性分析了25例经蝶手术治疗的急性垂体瘤卒中患者的临床及内分泌结果资料。13例在入院后3天内手术,22例在1 周内手术。结果 25例患者中术前有9例伴有垂体-甲状腺轴受损,14例伴有肾上腺功能低下,11例伴有性腺功能低下表现。术后分别有5 例、8例、7例得到恢复。对术后仍存在肾上腺皮质功能低下者、甲状腺功能低下者、性腺功能低下者分别给予相应激素替代治疗。结论急性垂体卒中多合并有垂体功能低下表现,早期手术有助于恢复正常垂体功能。对于术后仍存在垂体功能低下表现者应给予相应的激素替代治疗。
Objective To investigate the changes of pituitary function in patients with acute pituitary apoplexy before and after transsphenoidal surgery. Methods The clinical data and endocrine results of 25 patients with transsphenoidal surgery for acute pituitary apoplexy were retrospectively analyzed. Thirteen patients underwent surgery within 3 days after admission and 22 underwent surgery within 1 week. Results Among 25 patients, 9 cases had preoperative pituitary-thyroid axis damage, 14 cases had adrenal insufficiency, and 11 cases had hypogonadism. After surgery, there were 5 cases, 8 cases, 7 cases were restored. After surgery there are still adrenal insufficiency, hypothyroidism, hypogonadism were given the appropriate hormone replacement therapy. Conclusions Acute pituitary apoplexy combined with hypopituitarism showed that early surgery can help restore normal pituitary function. For postoperative pituitary dysfunction, there should still be given the appropriate hormone replacement therapy.