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本文采用24h动态血压监测（ABPM）评价卡托普利对28例10～12岁小儿肾实质性高血压的昼夜降压效果，随机分为2组口服卡托普利治疗。A组药物总量（2mg／kg）分2次在白天服用。B组药物总量分别于6：00，14：00，22：003次服用，服药前及服药4wk后分别进行ABPM。结果：A组白天血压下降，明显低于治疗前，但夜间血压与治疗前无差异B组昼夜血压下降平稳，白天与夜间血压均低于治疗前。
In this paper, 24-hour ambulatory blood pressure monitoring (ABPM) was used to evaluate the effect of captopril on 28 cases of renal parenchymal hypertension in children aged 12 to 12 years. The patients were randomly divided into two groups treated with captopril. A group of drugs (2mg / kg) divided into 2 times during the day. The total amount of drugs in group B was taken at 6:00, 14:00 and 22:00 respectively, and ABPM was taken before taking medicine and 4 weeks after taking medicine. Results: The daytime blood pressure in group A decreased significantly lower than that before treatment, but there was no difference between nighttime blood pressure and before treatment. The daytime and nighttime blood pressure decreased smoothly in group B, and the daytime and nighttime blood pressure were lower than before treatment.