Castleman病(CastlemanDisease,CD)系慢性淋巴组织增生性疾病,临床上颇为少见。临床类型可分为局灶性(L)和多中心性(M),组织学类型可分为透明血管型(HV)、浆细胞型(PC)及混合型(Mix)。局灶性者通常少有全身症状,且经病灶切除后预后良好;而多中心性尤其是浆细胞型(M/PC型CD)者则 Castleman disease (Castleman disease, CD) is a chronic lymphoproliferative disease, clinically rare. Clinical types can be divided into focal (L) and multicentric (M), histological types can be divided into transparent vascular type (HV), plasma cell type (PC) and mixed (Mix). Localized patients usually have few systemic symptoms and have a good prognosis after excision of the lesion; whereas those with multiple centers, especially plasmacytoid (M / PC type CD)