论文部分内容阅读
作者为研究肾内激肽的产生和肾素释放之间的相互关系,曾测定9名正常人和7例原发性醛固酮增多症病人肾静脉及其水平线之下的下腔静脉(ICV)中的血浆激肽浓度和血浆肾素活性(PRA)。正常受试者的年龄分布在30～50岁,其中男性5人和女性4人,全部主诉健康,无肾病史,仰卧收缩压均≤151mmHg、舒张压均≤95mmHg,以及全部在非卧位情况下作肾静脉导管插入术;同时在卧床至少90分钟后,自肘前静脉来血测定PRA;采集24/小时尿,测定肌酸酐、钠和醛固酮;这些正常受试者内源性肌酸酐清除率和血清钾是正常的,均无蛋白尿,以及24小时尿钠排泄量为107±19mmol。被选择的原发性醛固酮增多症病人的年龄分布在30～
The authors studied the relationship between renin production and renin release. Renal veins of 9 normal individuals and 7 patients with primary aldosteronism were assayed in the inferior vena cava (ICV) below their horizontal line Plasma kinin concentration and plasma renin activity (PRA). Normal subjects were aged 30 to 50 years old, of which 5 were males and 4 females, all complained of health, no history of kidney disease, supine systolic pressure were ≤ 151mmHg, diastolic blood pressure were ≤ 95mmHg, and all in the non-lying situation Undergoing renal venous catheterization; meanwhile, PRA was measured from the anterior venous blood from an elbow at least 90 minutes after bed rest; 24 / hour urine was collected for determination of creatinine, sodium and aldosterone; endogenous creatinine clearance was measured in these normal subjects Rate and serum potassium are normal, no proteinuria, and urinary sodium excretion 24 hours was 107 ± 19mmol. Selected primary aldosteronism in patients with age distribution in 30 ~