人乳头瘤病毒(HPV)感染是宫颈癌的根本致病因素,其中高危型HPV(HR-HPV)可引起95%以上的宫颈癌[1]。HPV检测不仅能够提高宫颈细胞学筛查的敏感性、预警病情发展情况、评估疗效及预后,而且能够延长HPV阴性而细胞学异常者的检查间隔期。目前,HPV检测已成为宫颈疾病的重要防癌筛查 Human papillomavirus (HPV) infection is the fundamental causative factor of cervical cancer, of which high-risk HPV (HR-HPV) can cause more than 95% of cervical cancer [1]. HPV testing can not only improve the sensitivity of cervical cytology screening, alert the development of the disease, assess the efficacy and prognosis, but also to extend the HPV-negative cytology abnormalities of those intervals. At present, HPV testing has become an important anti-cancer screening of cervical diseases