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很多报告指出,口服避孕药(OCA)可以改变血清铁、铜、锌的含量,也可改变金属蛋白即运铁球蛋白、血浆铜蓝蛋白、α_2~-巨球蛋白和白蛋白含量,并认为金属的变化反映了运输蛋白质的变化。作者选择了19～25岁的妇女22人,14人口服避孕药,试验结果证明,两组铁、铜、锌的吸收率平均都在13.7±12.3、57.4±17.7、及37.8±15.6%之间,无明显差异。OCA者每天吸收的Fe~(59)、Cu~(65)和Zn~(70)分别为每天平均11.5±3.5毫克、1.9±0.7毫克及11.0±3.4毫克,未服OCA者三者的吸收量每天平均值分别为10.3±1.9、2.1±0.7和11.3±3.0毫克,也无显著不同。对血清铁含量、血浆蛋白结合铁(TIBC)、血浆酮蓝蛋白及血浆白蛋白测定的结果,OCA者平均分别为116±28微克%、32
Many reports indicate that oral contraceptives (OCA) can change serum iron, copper, zinc content, but also can change the content of metalloprotein iron transport globulin, ceruloplasmin, α 2 macroglobulin and albumin, and that Changes in metals reflect changes in transport proteins. The authors selected 22 women aged 19 to 25 years and 14 oral contraceptives. The results showed that the absorption rates of iron, copper and zinc in the two groups averaged 13.7 ± 12.3, 57.4 ± 17.7 and 37.8 ± 15.6% respectively , No significant difference. The daily absorptions of Fe ~ (59), Cu ~ (65) and Zn ~ (70) by OCA were 11.5 ± 3.5 mg, 1.9 ± 0.7 mg and 11.0 ± 3.4 mg per day, respectively. The average daily values were 10.3 ± 1.9, 2.1 ± 0.7 and 11.3 ± 3.0 mg respectively, with no significant difference. The results of serum iron content, plasma protein-bound iron (TIBC), plasma ketonetin and plasma albumin were as follows: OCA OCs were 116 ± 28 μg%, 32