钩端螺旋体病(以下简称钩体病)是由致病性钩端螺旋体引起的一类传染病。钩端螺旋体具有分布范围广、寄生宿主多和菌型非常复杂等特点。过去认为,重度黄疸、肾功衰竭、皮肤粘膜广泛出血为本病的典型表现。实际上,这是一部分重症病的晚期表现;而对于钩体病大量的早期临床表现,历来很 Leptospirosis (hereinafter referred to as leptospirosis) is a group of infectious diseases caused by pathogenic Leptospira. Leptospira has a wide distribution, parasitic host and bacteria is very complex and so on. In the past that severe jaundice, renal failure, extensive skin and mucous membrane bleeding is the typical manifestation of the disease. In fact, this is part of the late manifestations of critically ill patients; and for the large number of early clinical manifestations of leptospirosis, has always been very