主动脉缩窄的临床特点是上肢与下肢间的动脉搏动及血压的梯度有差别。一侧或两侧上肢血压增高取决于缩窄发生的部位与锁骨下动脉的关系。高血压产生的基础是肾脏因素或是缩窄段本身使血管阻力增加的作用仍有争论。多数人认为主动脉缩窄使肾血液动力学改变,球旁小体受刺激,排泄肾素,血管紧张素及醛固酮增加,引起周围血管阻力及血容量增加,并增加了心脏搏出量。这是本病血压增高的主要因素.本症最终预后决定于解除主动脉缩窄。Maron等对 The clinical features of aortic constriction are differences in arterial pulsation and blood pressure gradient between upper and lower extremities. One or both of the upper extremity blood pressure increase depends on the site of narrowing and subclavian artery relationship. Hypertension is based on the renal factors or narrowing of the vascular resistance to increase their role is still controversial. Most people think that the aortic constriction changes the renal hemodynamics, the ball next to the body is stimulated, excretion of renin, angiotensin and aldosterone increased, causing increased peripheral vascular resistance and blood volume, and increased cardiac stroke volume. This is the main factor in this disease increased blood pressure.The final prognosis of this disease is determined by the lifting of aortic constriction. Maron et al