论文部分内容阅读
目的分析经阴道彩色多普勒超声联合血清糖链抗原125(CA125)、癌胚胎抗原(CEA)检测对卵巢癌诊断灵敏度及准确率。方法 62例卵巢癌患者为研究组,同期63例健康体检者为对照组,均行阴道彩色多普勒超声检查、血清CA125、CEA检测,对比三者联合诊断的灵敏度、特异度、准确率。结果研究组血清CA125、CEA水平高于对照组(P<0.05);三者联合诊的断灵敏度、特异度、准确率均高于阴道彩超、血清CA125、CEA单一诊断(P<0.05)。结论经阴道彩色多普勒超声联合血清CA125、CEA检测可提高卵巢癌诊断的灵敏度、特异度及准确率,且血清CA125、CEA水平在卵巢癌中呈高表达。
Objective To analyze the diagnostic sensitivity and accuracy of transvaginal color Doppler ultrasonography combined with serum carbohydrate antigen 125 (CA125) and carcinoembryonic antigen (CEA) in the diagnosis of ovarian cancer. Methods Totally 62 ovarian cancer patients were included in the study group. 63 healthy subjects were selected as the control group in the same period. All patients underwent vaginal color Doppler echocardiography. The serum CA125 and CEA levels were measured. The sensitivity, specificity and accuracy of the three methods were compared. Results The levels of serum CA125 and CEA in the study group were significantly higher than those in the control group (P <0.05). The sensitivity, specificity and accuracy of the combined diagnosis were higher than those of the vaginal ultrasound, serum CA125 and CEA alone (P <0.05). Conclusions Transvaginal color Doppler ultrasound combined with serum CA125 and CEA can improve the sensitivity, specificity and accuracy of diagnosis of ovarian cancer, and the serum CA125 and CEA levels are highly expressed in ovarian cancer.