最新研究显示α_1-抗胰蛋白酶缺乏症患者的健康状况不良与死亡的风险增大,这主要归因于气流受阻。来自于美国俄亥俄州 Cleveland 临床基金会的James K.Stoller 博士及其同事对此指出,该研究告诫临床医生α_1-抗胰蛋白酶缺乏是一重要的临床问题,气流阻塞是导致死亡率增加的主要因素;因而减小肺功能下降速率的干预治疗尤为重要。 Recent research shows that patients with alpha 1-antitrypsin deficiency have an increased risk of poor health and death, mostly due to obstruction of airflow. In this regard, Dr. James K. Stoller from the Cleveland Clinic Foundation in Ohio, Ohio, and colleagues point out that the study warned clinicians that alpha 1-antitrypsin deficiency is an important clinical issue and that airflow obstruction is a major contributor to increased mortality ; Thus intervention to reduce the rate of decline in lung function is particularly important.