目的探讨光动力学疗法治疗乳癌根治术后内乳区淋巴结转移的作用和方法。方法2005年6月至2005年12月,选择经内乳区淋巴结显像证实有内乳区淋巴结转移的12例乳癌患者,于胸骨旁肋间隙经穿刺针导入柱状激光光纤,进行光动力学照射。术后3个月再行内乳区淋巴结显像复查。激光仪波长630nm,光敏剂血卟啉剂量5mg/kg;柱状激光光纤,末端输出功率密度300mW/cm2,照射时间15min。结果9枚直径0.5~1.0cm内乳区淋巴结完全消失,4枚直径1.1~1.3cm明显缩小。结论光动力学照射内乳区淋巴结是治疗乳癌内乳区淋巴结转移的有效方法。 Objective To investigate the role and methods of photodynamic therapy in the treatment of lymph node metastasis after radical operation of breast cancer. Methods From June 2005 to December 2005, 12 patients with breast cancer who were confirmed by internal mammary lymph node imaging with internal mammary lymph node metastasis were selected. The columnar laser fiber was introduced into the parasternal rib space through the puncture needle for photodynamic therapy . Reconstruction of the internal mammary lymph node imaging 3 months after operation. Laser wavelength 630nm, photosensitizer hematoporphyrin dose 5mg / kg; columnar laser fiber, the end of the output power density 300mW / cm2, irradiation time 15min. Results Nine of 0.5 ~ 1.0cm diameter breast region lymph nodes completely disappeared, four diameter 1.1 ~ 1.3cm significantly reduced. Conclusion Photodynamic therapy of intra-breast lymph nodes is an effective method for the treatment of intra-breast lymph node metastases.