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将自杀基因转移到肿瘤细胞内能达到抗肿瘤效果,Ⅰ型单纯疮疹病毒胸音激酶(HSVI-TK)的代谢产物能把鸟苦的类似物丙氧鸟面转换成一磷酸形式,后者被细胞内的酶转化为三磷酸形式并在细胞分裂时结合到DNA中,从而阻止DNA的合成而导致细胞死亡。本实验目的是评价自杀基因疗法对?
Transfer of the suicide gene into tumor cells can achieve anti-tumor effects. The metabolites of type I simplex virus-thymus kinase (HSVI-TK) can convert the bird bitter analog propoxoside to a monophosphate form, the latter being Enzymes in cells convert to triphosphates and bind to DNA when cells divide, preventing DNA synthesis and causing cell death. The purpose of this experiment is to evaluate the suicide gene therapy pair?