难治性消化性溃疡的定义尚无统一标准,一般认为经合理的内科治疗3月溃疡来愈,或症状持续存在,或是反复发作者,称之为难治性消化性溃疡。难治性溃疡是临床上较为棘手的问题之一,其治疗应遵循个别化的原则,针对患者可能的致病因素、溃疡病 The definition of refractory peptic ulcer is no uniform standard, generally considered reasonable medical treatment of ulcers in March to more, or the symptoms persist, or repeated attacks, called refractory peptic ulcer. Refractory ulcer is one of the more difficult clinical problems, the treatment should follow the principle of individualized, for patients with possible risk factors, ulcer disease