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目的探讨重型颅脑损伤患者血糖水平与预后的关系。方法回顾性分析69例重型颅脑损伤患者,将其随机分为强化胰岛素治疗组(n=35)及常规胰岛素治疗组(n=34),强化组将24h平均血糖控制在5.0-8.0mmol/L之间,常规组将24h平均血糖控制在8.1-11.1mmol/L之间。结果强化治疗组患者预后明显好于常规治疗组,差异有统计学意义(P<0.05)。结论颅脑损伤后24h内的血糖峰值与颅脑损伤的伤情和预后密切相关,伤情越重,血糖升高越明显,预后也越差,将患者血糖水平控制在5.0-8.0mmol/L之间,可改善患者的预后。
Objective To investigate the relationship between blood glucose and prognosis in patients with severe craniocerebral injury. Methods A total of 69 patients with severe craniocerebral injury were retrospectively analyzed. Patients in intensive therapy group were randomly divided into intensive insulin treatment group (n = 35) and conventional insulin treatment group (n = 34) L between the conventional group 24h average blood glucose control in 8.1-11.1mmol / L between. Results Patients in the intensive treatment group had significantly better prognosis than the conventional treatment group (P <0.05). Conclusion The peak blood glucose within 24 h after craniocerebral injury is closely related to the injury and prognosis of craniocerebral injury. The heavier the injury is, the more obvious the increase of blood glucose and the worse the prognosis are. The patients’ blood glucose level is controlled at 5.0-8.0 mmol / L Between, can improve the patient’s prognosis.