Light and Electron Microscopic Observation of NT-LI Components in the Caudal Portion of the Fourth V

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Distribution of neurotensin-like immunoreactive(NT-LI)components in the caudalportion of the fourth ventricular floor was shown by immunocytochemistry.Under the light mi-croscopy,NT-LI neuronal bodies,fibers and terminals could be observed in the ependymal cell lay-er,and the processes of NT-LI neurons found in the nucleus of solitary tract(Sol)and area postrema(AP)could be traced into the ependymal cell layer.Under the electron microscopy,NT-positiveand-negative axons and terminals were found in the cavity of the fourth ventricle.Some labeled ter-minals formed synapse-like structure with the ependymal cells.The present results suggested thatthere might be cerebrospinal fluid(CSF)-contacting neurons containing neurotensin(NT)in the Soland AP,which might participate in forming brain-CSF neurohumoral circuits or in modulating theependymal activity. Distribution of neurotensin-like immunoreactive (NT-LI) components in the caudal discharge of the fourth ventricular floor was shown by immunocytochemistry. Under the light mi-croscopy, NT-LI neuronal bodies, fibers and terminals could be observed in the ependymal cell lay- er, and the processes of NT-LI neurons found in the nucleus of solitary tract (Sol) and area postrema (AP) could be traced into the ependymal cell layer. Under the electron microscopy, NT-positive and-negative axons and terminals were found in the cavity of the fourth ventricle. Home labeled ter-minals formed synapse-like structure with the ependymal cells. the present results suggested that that might might cerebrospinal fluid (CSF) -contacting neurons containing neurotensin (NT) in the Soland AP, which might participate in forming brain-CSF neurohumoral circuits or in modulating the ependymal activity.
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