【摘 要】
：
CpG ODN(CpG oligonucleotide,CpG寡脱氧核苷酸)是人工合成的含有非甲基化的胞嘧啶鸟嘌呤二核苷酸(CpG)的寡脱氧核苷酸(ODN),可模拟细菌DNA刺激多种哺乳动物包括人的免疫细胞
【机 构】
：
西安交通大学医学院第二附属医院血液科,
论文部分内容阅读
CpG ODN(CpG oligonucleotide,CpG寡脱氧核苷酸)是人工合成的含有非甲基化的胞嘧啶鸟嘌呤二核苷酸(CpG)的寡脱氧核苷酸(ODN),可模拟细菌DNA刺激多种哺乳动物包括人的免疫细胞。它能直接激活B细胞和单核细胞(巨噬细胞和树突状细胞),间接激活NK细胞和T细胞等多种免疫效应细胞,增
CpG ODN (CpG oligonucleotide) is a synthetic oligodeoxynucleotide (ODN) containing non-methylated cytosine guanine dinucleotide (CpG) that mimics multiple bacterial DNA stimuli Mammals include human immune cells. It can directly activate B cells and monocytes (macrophages and dendritic cells), indirect activation of NK cells and T cells and other immune effector cells, increased
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