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目的:总结妊娠期合并膀胱肿瘤的临床特点、诊疗对策、母婴结局以及探讨较为适当的处理方法。方法:对1例妊娠期合并膀胱肿瘤的患者进行影像学检查、实验室检查及膀胱镜检查,并于连续硬膜外腔麻醉下行剖宫产术及经尿道膀胱肿瘤切除术(TURBT术)。结果:剖宫产分娩出正常男婴,随后立即行TURBT术,其中TURBT手术时间20min,出血10ml,术后第7天出院,恢复良好,术后病理结果提示:尿路上皮癌,Ⅱ级。随访2年,未见疾病转移或复发。结论:妊娠期合并膀胱肿瘤临床上较为少见,对于其发生的机制尚未明确,其诊断方式的选择应避免使用可能致胎儿畸形的检查,对于其治疗需注意时机及治疗方案的选择。
OBJECTIVE: To summarize the clinical features, diagnosis and treatment strategies, maternal and infant outcomes and the more appropriate treatment of bladder tumor during pregnancy. Methods: One patient with bladder tumor during pregnancy was examined by imaging, laboratory and cystoscopy. Cesarean section and TURBT under continuous epidural anesthesia were performed. Results: The cesarean section gave birth to normal male infants. Immediate TURBT was performed. TURBT was performed for 20 minutes and the bleeding was 10ml. The patients were discharged on the 7th day after operation and recovered well. The postoperative pathological findings suggested urinary tract epithelial carcinoma, grade Ⅱ. Follow-up 2 years, no disease metastasis or recurrence. Conclusions: The clinical manifestations of bladder cancer in pregnancy are relatively rare. The mechanism of its occurrence is not yet clear. The choice of diagnosis should avoid the use of possible examination of fetal malformations, and should pay attention to the timing and treatment options.