肿瘤生物学研究认为,肿瘤是一类细胞增殖周期紊乱性疾病,表现为细胞增殖加速和凋亡障碍[1]。恶性肿瘤目前是危害人类健康最严重的一类疾病,乳腺癌是女性主要恶性肿瘤之一,全球每年约有120万妇女患乳腺癌,且近年有逐年上升的趋势,其发生、发展与细胞周期的改变及细胞凋亡的抑制? Tumor biology studies suggest that tumors are a group of disorders of the cell cycle of proliferation, manifested as accelerated cell proliferation and apoptosis [1]. Currently, malignant tumors are one of the most serious human health hazards. Breast cancer is one of the major malignant tumors in women. About 1.2 million women worldwide are suffering from breast cancer each year. In recent years, there is a trend of rising year by year. The occurrence, development and cell cycle Changes and inhibition of apoptosis?