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目的探讨药学干预对抗菌药物处方评价及药物经济学的影响,为临床提供借鉴资料。方法选择我院2009年1200张处方作为对照组、以2004年版本国家基本药物目录为点评基础;选择我院2010年1200张处方作为实验组、以2009年版本国家基本药物目录为基础+处方点评制度实施后的药学主动干预。结果实验组抗菌药物的使用在适应证、给药途径、给药剂量、溶媒选择、药敏试验和医药成本与对照组比较均明显得到改善(P<0.05)。结论通过处方点评等干预手段,可以使抗菌药物使用更加安全、合理,并对降低医疗成本起到较好的作用,值得临床关注。
Objective To investigate the influence of pharmacy intervention on prescription evaluation and pharmacology of antimicrobial agents and provide references for clinical application. Methods The 1200 prescriptions in our hospital were selected as the control group in 2009, and based on the 2004 version of the national essential drugs list, the 1,200 prescriptions in our hospital were selected as the experimental group and the 2009 version of the national essential drugs list as the basis. Pharmacological intervention after the implementation of the system. Results The use of antimicrobial agents in the experimental group was significantly improved (P <0.05) in indications, route of administration, dosage, vehicle selection, drug sensitivity test and medical costs compared with the control group. Conclusions The prescriptions and other interventions can make the use of antimicrobials safer and more reasonable, and play a good role in reducing medical costs. It is worthy of clinical attention.