脑益嗪体内给药能显著地抑制血小板聚集,但对动脉环前列环素(PGI_2)的产生和血小板血栓素A_2(TXA_2)的释放无作用,其抗血栓形成的作用看来不是通过对TXA_2/PGI_2系统的影响而发挥的;毛冬青甲素静脉注射,非常显著地抑制血小板聚集、抑制血小板TXA_2的释放,但不影响动脉环PGI_2的产生,生物测定法和放射免疫分析法所得结果相平行,提示毛冬青甲素可能是一种血栓素A_2合成酶抑制剂。 Cerebrospiri in vivo administration can significantly inhibit platelet aggregation, but the role of prostacyclin (PGI_2) and platelet release of thromboxane A_2 (TXA_2) has no effect, its antithrombotic effect does not seem to TXA_2 / PGI_2 system; Maoolin a intravenous injection of a very significant inhibition of platelet aggregation, inhibition of platelet TXA_2 release, but does not affect the PGI_2 artery production, bioassay and radioimmunoassay results parallel , Suggesting that haloterol may be a thromboxane A_2 synthase inhibitor.